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When KBs concentrations exceed 4 mmol/L, they become the CNSs primary energy source [26]

[PubMed: 30689447] (70 year old woman developed seizures within 30 minutes after mistakenly taking an industrial form of ALA [4500 mg] with metabolic acidosis, lactic acidosis [14.9 mmoL], decrease in platelets [140,000 decreasing to 73,000/uL], and hemodynamic instability, responding to supportive therapy within several days)

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